This single-center, non-randomized, parallel-group, clinical trial was conducted on 66 diagnostic hysteroscopy candidates who were selected by convenience sampling at Fatemieh Hospital, in Hamadan, Iran, in 2021.
Results: The mean
pain score during recovery and the need for
analgesic injections was found to be significantly higher in the GA group compared to that in the SPA group (
pain: 3.77 ± 2.25 vs. 0.10 ± 0.30, P < 0.001), (
analgesic: 50 vs. 0%, P < 0.001) and PB group (
pain: 3.77 ± 2.25 vs. 0.90 ± 1.37, P < 0.001), (
analgesic 50 vs. 10%, P < 0.001), respectively. However, no statistically significant difference was observed between the mean
pain score between SPA and PB groups (0.10 ± 0.30 vs. 0.90 ± 1.3, P = 0.661). In addition, there were no significant differences between groups on
nausea/
vomiting after operation (P = 0.382). In adjusted regression analysis (adjusting for age, weight, gravid, abortion, and cause of hysteroscopy), the odds ratio (OR) of
pain score during recovery was increased in PB (OR: 4.471, 95% CI: 1.527-6.156, P = 0.018) and GA (OR: 8.406, 95% CI: 2.421-9.195, P = 0.001) groups compared with the SPA group. However, in adjusting based on times of surgery duration,
anesthesia duration, recovery and return of motor function, the
ORs of
pain score between groups was not statistically significant.
Conclusion: Despite reduced
pain during recovery in patients receiving SPA, duration of
anesthesia, recovery period, and return of motor function were significantly prolonged compared to those receiving PB or GA. It seems that PB with less recovery time and faster return of motor function than SPA and also mild
pain during recovery compared to GA can be a good option for hysteroscopy.
Clinical trial registration: http://www.irct.ir, identifier IRCT20120915010841N26.