Abstract | BACKGROUND: OBJECTIVE: The purpose of this study was to determine the frequency and settings in which BiCSD was used in a tertiary referral center with expertise in LCSD. METHODS: RESULTS: Only 11 patients (4.7%; 6 females [55%]) had BiCSD at our institution. Patients who received BiCSD trended toward being younger at diagnosis (6 ± 15 years vs 14 ± 13 years; P = .06) and being more likely to be symptomatic (73% vs 53%; P = .07) than the larger LCSD-only cohort. Continued CEs post-LCSD (3.8 CEs per patient on average) was the predominant determinant to return for BiCSD. Over 60 combined years of follow-up, 4 patients have not had a CE post-BiCSD while the other 7 patients average 3.6 nonlethal CEs. CONCLUSION: Less than 5% of all patients receiving denervation therapy underwent BiCSD. When BiCSD was chosen, it was almost always done in a staged sequential manner beginning with LCSD first and when driven by the arrhythmogenicity of the LQTS substrate, despite otherwise optimized guideline-directed therapies.
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Authors | Kathryn E Tobert, J Martijn Bos, Christopher Moir, Stephanie F Polites, Michael J Ackerman |
Journal | Heart rhythm
(Heart Rhythm)
Vol. 20
Issue 7
Pg. 1033-1038
(Jul 2023)
ISSN: 1556-3871 [Electronic] United States |
PMID | 36934983
(Publication Type: Journal Article)
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Copyright | Copyright © 2023 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved. |
Topics |
- Female
- Humans
- Heart
- Long QT Syndrome
(diagnosis, surgery, etiology)
- Sympathectomy
(adverse effects)
- Death, Sudden, Cardiac
(etiology)
- Electric Countershock
- Retrospective Studies
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