Long-term effects of combined brilliant blue G and xenon light induced retinal toxicity following macular hole repair surgery.

Abstract

BACKGROUND:

The purpose of this study was to look at the long-term effects of retinal phototoxicity after macular hole repair surgery using xenon endolight illumination and Brilliant blue G (BBG) dye.

CASE PRESENTATION:

An elderly man in his late seventies underwent para plana vitrectomy with BBG dye to repair an idiopathic full-thickness macular hole (MH) in his right eye. Prior to macular hole surgery, his visual acuity in the right eye was 6/60, N24 at the time of presentation. The MH closed with type 1 closure immediately after surgery, but there was extensive damage to the outer retinal layers and retinal pigment epithelium (RPE) at the macula, resulting in a reduction in visual acuity to 2/60. We presumed that the combination of BBG and xenon light, is the probable reason of retinotoxicity in the current patient. There was a progressive increase in the area of retinal and RPE layer damage and choroidal thinning over a 4-year period.

CONCLUSION:

Due to combined BBG-induced dye and endoilluminator toxicity, a rare case of continuously progressing RPE layer damage with choroidal thinning over a long follow-up interval was described. Such long-term effects of BBG and endolight induced retinotoxicity have not been reported in the literature, to the best of our knowledge.

• Authors: Ramesh Venkatesh, Rubble Mangla, Shama Sharief, Jay Chhablani
• Journal: BMC ophthalmology (BMC Ophthalmol) Vol. 23 Issue 1 Pg. 57 (Feb 09 2023) ISSN: 1471-2415 [Electronic] England
• PMID: 36759787 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2023. The Author(s).

Chemical References

• coomassie Brilliant Blue
• Xenon
• Rosaniline Dyes

Topics

• Male
• Humans
• Aged
• Retinal Perforations (surgery)
• Xenon (toxicity)
• Rosaniline Dyes (toxicity)
• Retina
• Vitrectomy (adverse effects, methods)
• Eye Diseases (surgery)
• Tomography, Optical Coherence
• Retrospective Studies