Brentuximab-Induced Colitis in a Non-Stem-Cell Transplant Patient.

Abstract

Many chemotherapeutic agents have been associated with drug-induced colitis (DIC). With newer agents' expansion of approval as first-line therapy for common cancers, it is important to be cognizant of their association with DIC. We present a case of brentuximab-associated DIC in an elderly woman with CD30+ Hodgkin lymphoma. Brentuximab's association with DIC was suspected by others in the literature, but a history of stem-cell transplant in them would blur the association with graft-vs-host disease. Lack of stem-cell transplant in our patient makes the link between brentuximab and DIC unambiguous.

• Authors: Sareena Ali, Sufyan AbdulMujeeb, Ahmed Khattab, Nahren Asado, Marc Fine
• Journal: ACG case reports journal (ACG Case Rep J) Vol. 10 Issue 1 Pg. e00974 (Jan 2023) ISSN: 2326-3253 [Print] United States
• PMID: 36713279 (Publication Type: Case Reports)
• Copyright: © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.