Abstract | RATIONALE: PATIENT CONCERNS: DIAGNOSIS AND INTERVENTIONS: Having excluded infectious, epileptic and vascular causes of the acute neurologic syndrome of our patient, given the improvement and full recovery after discontinuation of cotrimoxazole, we hypothesized a DIAM. OUTCOMES: After discontinuation of cotrimoxazole, in 48 hours the patient had a full recovery. LESSONS: Although DIAM can be easily managed with the withdrawal of the causative drug, it can be difficult to recognize if it is not included in the differential diagnosis. An antimicrobial stewardship program with a strict monitoring of patients by infectious disease specialists is essential, not only to optimize the appropriate use of antimicrobials, but also to improve patient outcomes and reduce the likelihood of adverse events.
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Authors | Giulia Pata, Marco Montagna, Emanuele Bosi, Alberto Davalli, Patrizia Rovere Querini |
Journal | Medicine
(Medicine (Baltimore))
Vol. 102
Issue 1
Pg. e32475
(Jan 06 2023)
ISSN: 1536-5964 [Electronic] United States |
PMID | 36607874
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. |
Chemical References |
- Trimethoprim, Sulfamethoxazole Drug Combination
- Anti-Infective Agents
- Anti-Bacterial Agents
- Oxacillin
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Topics |
- Female
- Humans
- Middle Aged
- Trimethoprim, Sulfamethoxazole Drug Combination
(adverse effects)
- Meningitis, Aseptic
(chemically induced, diagnosis)
- Anti-Infective Agents
- Anti-Bacterial Agents
(adverse effects)
- Oxacillin
(adverse effects)
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