Abstract | Purpose: To investigate the change pattern of ocular perfusion pressure ( OPP) and intra-ocular pressure (IOP) after short-term and long-term aerobic exercise. Methods: In this prospective, single-masked, randomized clinical trial, 123 patients with a primary open angle glaucoma that locally used prostaglandin analog alone were randomly divided into the exercise and control groups. In the short-term study, all individuals underwent a cycling exercise at moderate intensity (20% Wmax for 10 minutes) and high intensity (60% Wmax for 5 minutes). During the long-term study, the exercise group is characterized by regular jogging exercise lasting for 30 minutes during 6: 00-10: 00 in the morning for 3 months, with the exercise frequency of at least 20 times per month, and with the intensity reflected by the target heart rate. The control group is designed as a group with irregular exercise. Results: After short-term aerobic exercise, IOP significantly decreased, whereas the ocular perfusion pressure ( OPP) significantly increased. The decreasing amplitude of IOP is related to the baseline of IOP, the intensity of exercise, gender, and so on. After 3 months of long-term exercise, the changes in the IOP level of the exercise group indicated a decreasing trend. Conclusion: The significant decrement of IOP and the increment of OPP suggest that aerobic exercise is beneficial for patients with primary open-angle glaucoma and appropriate aerobic exercise is appropriate in treating glaucoma patients. Trial registration: ChiCTR, ChiCTR-TRC-10001055. Registered one October 2010-Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj = 8483.
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Authors | Qiu-Yan Ma, Jian Zhou, Yu-Xin Xue, Yan-Ting Xia, Jian-Guo Wu, Ying-Xin Yang |
Journal | Indian journal of ophthalmology
(Indian J Ophthalmol)
Vol. 70
Issue 12
Pg. 4228-4234
(12 2022)
ISSN: 1998-3689 [Electronic] India |
PMID | 36453320
(Publication Type: Randomized Controlled Trial, Journal Article)
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Topics |
- Humans
- Exercise
- Glaucoma, Open-Angle
(therapy)
- Intraocular Pressure
- Perfusion
- Prospective Studies
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