Glucose emission spectra through mid-infrared passive spectroscopic imaging of the wrist for non-invasive glucose sensing.

Abstract

Non-invasive blood glucose sensing can be achieved using mid-infrared spectroscopy, although no practical device based on this method has yet been developed. Here, we propose mid-infrared passive spectroscopic imaging for glucose measurements from a distance. Spectroscopic imaging of thermal radiation from the human body enabled, for the first time in the world, the detection of glucose-induced luminescence from a distance. In addition, glucose emission spectra of the wrist acquired at regular intervals up to 60 min showed that there was a strong correlation between the glucose emission intensity and blood glucose level measured using an invasive sensor. Thus, the new technology proposed here is expected to be applied to real-time monitoring of diabetic patients to detect hypoglycemic attacks during sleep and to detect hyperglycemia in a population. Moreover, this technology could lead to innovations that would make it possible to remotely measure a variety of substances.

• Authors: Tomoya Kitazaki, Yusuke Morimoto, So Yamashita, Daichi Anabuki, Shiori Tahara, Akira Nishiyama, Kenji Wada, Ichiro Ishimaru
• Journal: Scientific reports (Sci Rep) Vol. 12 Issue 1 Pg. 20558 (11 29 2022) ISSN: 2045-2322 [Electronic] England
• PMID: 36446832 (Publication Type: Journal Article)
• Copyright: © 2022. The Author(s).

Chemical References

• Glucose
• Blood Glucose

Topics

• Humans
• Wrist
• Glucose
• Blood Glucose
• Wrist Joint
• Spectrophotometry, Infrared