Collagenous Gastoduodenitis in the Form of a Gastric Ulcer.

Abstract

Collagenous gastroduodenitis is a rare gastrointestinal disease diagnosed histologically by subepithelial collagen deposition in the lamina propria. Its clinical presentation is diverse. The authors encountered a 17-year-old female patient who complained of epigastric pain. Endoscopy revealed several deep ulcers in the gastric body. The gastric mucosa around the ulcer showed diffuse fine nodularity in the shape of cobblestones with open-type atrophy. The duodenal mucosa showed nodular lesions similar to those of the gastric mucosa. The gastric ulcer healed completely with proton pump inhibitor treatment. The patient was followed up, showing no remarkable mucosal change of stomach or duodenum for several years. Collagenous gastroduodenitis was diagnosed by repeated histologic examinations. This paper reports a rare case of chronic collagen gastritis with deep gastric ulcer and its long-term clinical progress.

• Authors: In Hyoung Choi, Yu Kyung Cho, Jun Young Park, Donghoon Kang, Jae Myung Park, Myung-Gyu Choi
• Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi (Korean J Gastroenterol) Vol. 80 Issue 5 Pg. 225-228 (11 25 2022) ISSN: 2233-6869 [Electronic] Korea (South)
• PMID: 36426557 (Publication Type: Case Reports)

Chemical References

• Collagen

Topics

• Female
• Humans
• Adolescent
• Stomach Ulcer (complications, diagnosis, pathology)
• Gastritis (complications, diagnosis, drug therapy)
• Gastric Mucosa (pathology)
• Collagen
• Endoscopy, Gastrointestinal
• Ulcer