Abstract | BACKGROUND: OBJECTIVE: To report preliminary data on this procedure and its safety and efficacy for treating TLE. METHODS: This consecutive case series study was conducted between October 2020 and September 2021. Patients with TLE underwent FATL by minicraniotomy with a diameter of 3 cm. Surgery duration, postoperative complications, and seizure control are described herein. Seizure outcomes were classified using Engel classifications. RESULTS: A total of 25 patients undergoing FATL for TLE were enrolled. The median epilepsy duration was 8 years. The median surgery duration was 165 min. The median blood loss was 100 mL. The median postoperative hospital stay was 8 days. No deaths occurred after surgery. Only 1 patient presented with a cerebrospinal fluid disorder that was successfully treated using a ventriculoperitoneal shunt. At the last follow-up, 23 patients (92%) were seizure-free (Engel-Ia), 1 patient remained substantially improved (Engel-II), and 1 patient obtained worthwhile seizure reduction (Engel-III). CONCLUSION: Our pilot study suggests that FATL is a viable surgical therapy for TLE. This method has the advantages of minimal invasiveness and high seizure-free rate. A controlled trial is warranted to verify the efficacy and safety of FATL comparing with anterior temporal lobectomy.
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Authors | Yong Liu, Yutao Ren, Qiang Meng, Hao Wu, Shan Dong, Huanfa Li, Xiaofang Liu, Kuo Li, Changwang Du, Hua Zhang |
Journal | Operative neurosurgery (Hagerstown, Md.)
(Oper Neurosurg (Hagerstown))
Vol. 24
Issue 1
Pg. 111-118
(01 01 2023)
ISSN: 2332-4260 [Electronic] United States |
PMID | 36331213
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © Congress of Neurological Surgeons 2022. All rights reserved. |
Topics |
- Humans
- Anterior Temporal Lobectomy
(methods)
- Epilepsy, Temporal Lobe
(surgery, complications)
- Pilot Projects
- Seizures
(surgery)
- Treatment Outcome
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