Abstract | Background: Methods: Results: After a median of 10.75-year follow-up, 637 incident hypertension cases were identified. The restricted cubic spline showed that the lipid risk score had a positive linear correlation with hypertension (P< 0.001). Among people< 55 years, with every increase of 0.94 in lipid risk score, the risk of hypertension increased by 37% (adjusted HR [95%CI]: 1.369 [1.164-1.610]). This association was not modified by overweight or obesity. Conclusions: The integrated lipid risk score, independent of traditional risk factors, has a significantly predictive effect on hypertension in people younger than 55 years. This finding may aid in identifying high-risk individuals for hypertension, as well as facilitating early intervention and management to reduce adverse cardiovascular events. Comprehensive lipid management should be attached importance in the prevention and control of hypertension.
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Authors | Hankun Xie, Qian Zhuang, Jialing Mu, Junxiang Sun, Pengfei Wei, Xianghai Zhao, Yanchun Chen, Jiayi Dong, Changying Chen, Lai Wei, Yunjie Yin, Song Yang, Chong Shen |
Journal | Frontiers in endocrinology
(Front Endocrinol (Lausanne))
Vol. 13
Pg. 916951
( 2022)
ISSN: 1664-2392 [Print] Switzerland |
PMID | 36246874
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2022 Xie, Zhuang, Mu, Sun, Wei, Zhao, Chen, Dong, Chen, Wei, Yin, Yang and Shen. |
Chemical References |
- Cholesterol, HDL
- Cholesterol, LDL
- Triglycerides
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Topics |
- Cholesterol, HDL
- Cholesterol, LDL
- Dyslipidemias
(epidemiology)
- Humans
- Hypertension
(epidemiology, etiology)
- Middle Aged
- Prospective Studies
- Risk Factors
- Triglycerides
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