Abstract | BACKGROUND: Males have higher weight and length at birth than females. AIM: SUBJECTS AND METHODS: RESULTS: Weight and length at birth were lower in TS and mixed GD when compared to XY and XX DSD cases. In turn, patients with increased androgen action (117 cases) had higher weight and length at birth when compared to those with absent (108 cases) and decreased (68 cases) production/action. In birthweight, there was a negative influence of the 45,X/46,XY karyotype and a positive influence of increased androgen and gestational age. In birth length, there was a negative influence of the 45,X and 45,X/46,XY karyotypes and also a positive influence of increased androgen and gestational age. CONCLUSIONS: The sex dimorphism of weight and length at birth could possibly be influenced by intrauterine androgenic action.
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Authors | D S R Amais, T E R da Silva, B A Barros, J G R de Andrade, S H V de Lemos-Marini, M P de Mello, A P Marques-de-Faria, T N Mazzola, M S Guaragna, H Fabbri-Scallet, T A P Vieira, N L Viguetti-Campos, A M Morcillo, O Hiort, A T Maciel-Guerra, G Guerra-Junior |
Journal | Annals of human biology
(Ann Hum Biol)
Vol. 49
Issue 7-8
Pg. 274-279
(Dec 2022)
ISSN: 1464-5033 [Electronic] England |
PMID | 36218438
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Male
- Child
- Infant, Newborn
- Female
- Humans
- Retrospective Studies
- Androgens
- Sex Characteristics
- Cross-Sectional Studies
- Androgen-Insensitivity Syndrome
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