Abstract | Background and Aim: Methods: A prospective study was conducted in the liver intensive care unit of a quaternary teaching institute. Baseline and follow-up data pertaining to mNUTRIC score, clinical, hemodynamic, biochemical, nutritional parameters, mechanical ventilation, length of ICU stay, and development of sepsis were collected. Correlation between mNUTRIC score and its modulation by nutritional adequacy was determined. Results: One hundred and fifty patients were enrolled. Out of these, 116 (77%) had a high NUTRIC score (HNS) and 34 (23%) had a low NUTRIC score (LNS). Patients with HNS had higher mortality (54% vs. 10%; P = 0.008), longer mechanical ventilation (P = 0.02), and high incidence of sepsis (32% vs. 2.6%; P = 0.002) compared to LNS. The probability of survival increased with increase in nutritional adequacy (P < 0.01) in patients with HNS. Conclusion: Relevance for Patients:
Critically ill patients with cirrhosis who are at a higher nutritional risk as identified by the mNUTRIC score may have a better survival benefit if higher calorie and protein adequacy are achieved in the ICU.
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Authors | Harshita Tripathi, Jaya Benjamin, Rakhi Maiwall, Puneet Puri, Puja Bhatia Kapoor, Varsha Shasthry, Vandana Saluja, Prashant Agrawal, Guresh Kumar, Yogendra Kumar Joshi, Shiv Kumar Sarin |
Journal | Journal of clinical and translational research
(J Clin Transl Res)
Vol. 8
Issue 5
Pg. 425-433
(Oct 31 2022)
ISSN: 2424-810X [Electronic] Singapore |
PMID | 36212700
(Publication Type: Journal Article)
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Copyright | Copyright: © 2022 Author(s). |