Abstract | PURPOSE: MATERIALS AND METHODS: In this prospective observational pilot study, data were collected at baseline and 1-year following the ambulatory recruitment of patients in the Department of Respiratory Medicine at the National Hospital Organization Nishiniigata Chuo Hospital. We recruited 96 patients with chronic respiratory disease undergoing LTOT, and 55 patients who completed a 1-year follow-up were finally included. RESULTS: Multivariate logistic regression analysis revealed that Montreal Cognitive Assessment score reduction (a measure of cognitive decline) was associated with Barthel index score reduction (a measure of ADL) at 1-year follow-up (odds ratio: 3.98; 95% confidence interval: 1.16 - 13.69; p = 0.02). CONCLUSION: A progression of cognitive decline in patients undergoing LTOT may affect ADL decline. An early detection of cognitive decline in patients undergoing LTOT is essential for ADL maintenance in rehabilitation practice.IMPLICATIONS FOR REHABILITATIONPatients undergoing long-term oxygen therapy (LTOT) present with progressive cognitive decline.Cognitive decline progression is associated with a decline in activities of daily living in patients undergoing LTOT.A periodic cognitive assessment is important in rehabilitation practice for the early detection of progressive cognitive decline in patients undergoing LTOT.
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Authors | Hiroki Annaka, Tomonori Nomura, Hiroshi Moriyama |
Journal | Disability and rehabilitation
(Disabil Rehabil)
Vol. 45
Issue 21
Pg. 3493-3499
(10 2023)
ISSN: 1464-5165 [Electronic] England |
PMID | 36171683
(Publication Type: Observational Study, Journal Article)
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Chemical References |
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Topics |
- Humans
- Activities of Daily Living
- Prospective Studies
- Pilot Projects
- Cognitive Dysfunction
(therapy)
- Oxygen
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