Role of preoperative CT angiography with multimodality imaging reconstruction to perform laparoscopic Complete Mesocolic Excision (CME) and Central Vascular Ligation (CVL) in right-sided colon cancer: Is it really useful? A prospective clinical study.

Abstract

BACKGROUND:

The concept of complete mesocolic excision (CME) and central vascular ligation (CVL) in right colonic resections appears to improve the oncological outcomes. The highest rate of complications reported in the literature in patients undergoing CME is related to difficult surgical manuevers and intraoperative bleeding due to the central vascular dissection.

METHODS:

We used preoperative findings obtained with the CT angiography, multiplanar reformation (MPR), maximum intesity projection (MIP) and 3D volume rendering (VR) technique to verify if this preoperative radiological assessment had significant benefits regarding the difficulty of dissection of the embryological planes, the identification of vascular structures and central lymph nodes with reduction in mean operative time, intraoperative complications and better short-term outcomes versus standard contrast enhanced CT scan. We also have administered a questionnaire to investigate the subjective responses on the degree of difficulty of the surgical procedure both by the surgical team expert in CME and by a group of young surgeons.

RESULTS:

Statistical analysis showed that overall operative time was significant shorter in patients underwent to radiological assessment (224,5 min; range 160-300 versus 252,6 min; range 200-340; p-value 0.023) with a significant lower rate of intraoperative complication (2.7% versus 4.2%; p-value 0.043). No differences were reported with respect to blood loss, conversion rate, anastomotic leakage or other surgical results. Analysis of the questionnaire underlined a progressive awareness of the correspondence between the radiological imaging and the surgical field.

CONCLUSION:

The possibility of identifying the characteristics and course of the vascular structures along the axis of the superior mesenteric vessels certainly increases the surgeon's knowledge of the operating field, making him more confident with surgical maneuvers and significantly reducing the duration of the operating time and intraoperative complications.

• Authors: Giorgio Romano, Giuseppe Di Buono, Massimo Galia, Francesco Agnello, Gabriele Anania, Mario Guerrieri, Marco Milone, Gianfranco Silecchia, Salvatore Buscemi, Antonino Agrusa
• Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology (Eur J Surg Oncol) Vol. 49 Issue 1 Pg. 209-216 (01 2023) ISSN: 1532-2157 [Electronic] England
• PMID: 36002353 (Publication Type: Journal Article)
• Copyright: Copyright © 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

Topics

• Humans
• Male
• Colonic Neoplasms (diagnostic imaging, surgery)
• Computed Tomography Angiography
• Prospective Studies
• Colectomy (methods)
• Ligation (methods)
• Laparoscopy (methods)
• Mesocolon (diagnostic imaging, surgery)
• Lymph Node Excision (methods)
• Intraoperative Complications
• Treatment Outcome