Coronavirus disease-19 (COVID-19) caused a global pandemic burden, affecting hundreds of thousands of individuals, having life-threatening outcomes.
Traditional Chinese Medicine plays a crucial role in the treatment of patients with
COVID-19. The purpose of this study was to investigate the efficacy of combined
therapy of qingfeiPaidu (QFPD)
capsule and
lianhuaqingwen (LHQW)
capsule nursing interventions in the treatment of patients with
COVID-19. A total of 318 patients with
COVID-19 were enrolled and randomly received QFPD (n = 106), LHQW (n = 106), and QFPD-LHQW (n = 106). The clinical characteristics of
COVID-19, the total lung severity scores, and blood laboratory indices were recorded in each patient in each group before treatment and at the end of treatment. The outcomes demonstrated that QFPD-LHQW group shortened the length of hospitalization, decreased
C-reactive protein,
creatine kinase,
creatine kinase-myocardial band,
lactate dehydrogenase, and blood
urea nitrogen levels, and improved clinical symptoms,
pulmonary inflammation, and prognosis. At the end of treatment,
inflammation, immune function, circulating white blood cells, total lymphocyte count, and
glutamic-oxaloacetic transaminase levels improved dramatically in 3 groups compared with baseline. All patients met the discharge criteria after 30-day treatment in 3 groups. Combined
therapy of QFPD and LHQW demonstrated significant anti-inflammatory effects compared with those of only QFPD or LHQW in patients with mild and moderate
COVID-19. The combined
therapies may alleviate clinical symptoms of
COVID-19 patients by improving
inflammation and immune function.