Abstract | BACKGROUND: CASE PRESENTATION: A 65-year-old Chinese male with an eight-year history of KD was admitted to our hospital with complaints of dyspnea and expectoration for one month. Laboratory examination showed a considerable elevation in the serum eosinophil count and total IgE and IgG4 levels. Chest enhanced computed tomography showed filling defects in the right pulmonary artery and a nodule in the left inferior lobe. Pancreatic enhanced magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography showed a swollen pancreatic tail and local stricture of the pancreatic duct section of the common bile duct. Enhanced MRI of the pituitary gland showed thickening of the pituitary stalk. Additionally, immunohistochemistry of the specimens collected eight years prior revealed IgG4-positive cells. Following the diagnosis of IgG4-RD with KD, glucocorticoids with immunosuppressants were initiated; there was a prompt improvement in the patient's condition. One-year post-discharge, the patient underwent wedge-shaped resection of the lung due to enlargement of the pulmonary nodule, and the pathology revealed lung squamous carcinoma. CONCLUSIONS:
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Authors | Ye Lu, Junxiu Liu, Hengyi Yan, Wei Feng, Li Zhao, Yu Chen |
Journal | BMC pulmonary medicine
(BMC Pulm Med)
Vol. 22
Issue 1
Pg. 305
(Aug 09 2022)
ISSN: 1471-2466 [Electronic] England |
PMID | 35945530
(Publication Type: Case Reports, Journal Article)
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Copyright | © 2022. The Author(s). |
Chemical References |
- Immunoglobulin G
- Immunoglobulin E
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Topics |
- Aftercare
- Aged
- Asthma
(complications)
- Carcinoma
- Diabetes Insipidus, Neurogenic
(complications)
- Humans
- Immunoglobulin E
- Immunoglobulin G
- Immunoglobulin G4-Related Disease
(complications, diagnosis)
- Kimura Disease
- Lung Neoplasms
(complications, diagnosis)
- Male
- Patient Discharge
- Pulmonary Embolism
(complications)
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