Background: To analyze the factors influencing lower limb
lymphedema (LLL) after
cervical cancer surgery and provide a scientific reference for its effective prevention and control. Methods and Results: Patients at a tertiary
tumor hospital between January 2010 and January 2020 who received surgical treatment for
cervical cancer were included in this study. Patients were divided into
lymphedema case group (n = 253) and control group (n = 506) according to
lymphedema occurrence, and univariate and multivariate analyses were used to analyze the factors influencing the occurrence of LLL after
cervical cancer surgery. Multifactor conditional logistic regression analysis revealed that risk factors for
lymphedema occurrence included body mass index, level of education, the presence of preoperative
radiotherapy and
chemotherapy,
radiotherapy within 3 months after postoperative
chemoradiotherapy, emergence of
coronary heart disease within 3 months,
vaginal disease, occurrence of postoperative complications,
cervical cancer diagnosis before the manifestation of menstrual abnormalities, and a history of previous surgery. Conclusion: Postoperative LLL after
cervical cancer surgery is a chronic progressive disease, and no cure for LLL has been identified. Thus, determining the risk factors associated with LLL occurrence after uterine and
cervical cancer surgery and the development of targeted prevention and early intervention strategies is urgently needed.