Retinal misregistration and effect of surgery on its improvement in patients with epiretinal membrane.

Abstract

PURPOSE:

To evaluate the prevalence of retinal misregistration, that is, misalignment of retinal elements that affect central and peripheral fusion, and the effect of surgery in patients with epiretinal membrane (ERM).

METHODS:

This prospective interventional case-series was performed on 32 patients with symptomatic ERM with the complaint of binocular diplopia or decreased visual acuity. After the diagnosis of ERM, optotype frame, synoptophore, and lights on-off tests were used to evaluate retinal misregistration. Patients with severe symptoms underwent surgery and were followed for 3 months.

RESULTS:

Of the 32 patients, 6 (19%) had preoperative diplopia. Optotype frame, synoptophore, and lights on-off tests had positive results in 20 (63%), 19 (63%), and 11 (34%) cases, respectively. Of the 6 diplopia cases, 5 showed positive results in all 3 tests and 1 was positive on optotype frame and synoptophore testing. Of the 26 cases without diplopia, 15 (58%) showed positive results in at least one test, including 6 (23%) in all three tests, 6 (23%) in two tests, and 3 (12%) in only one test. Ten patients underwent surgery. Postoperatively, all patients had negative lights on-off test, but optotype frame and synoptophore tests were negative in eight patients (80%). Two cases (20%) had postoperative diplopia, including 1 case with postoperative new-onset diplopia.

CONCLUSIONS:

The prevalence of retinal misregistration was higher than the rate of diplopia. Surgery improved diplopia and results of tests of retinal misregistration.

• Authors: Arash Mirzaei, Mohammad Reza Akbari, Abdulrahim Amini, Arash Mirmohammadsadeghi, Hassan Khojasteh
• Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus (J AAPOS) Vol. 26 Issue 4 Pg. 179.e1-179.e5 (08 2022) ISSN: 1528-3933 [Electronic] United States
• PMID: 35842076 (Publication Type: Journal Article)
• Copyright: Copyright © 2022 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.

Topics

• Diplopia (diagnosis, epidemiology, surgery)
• Epiretinal Membrane (diagnosis, surgery)
• Humans
• Prospective Studies
• Retrospective Studies
• Tomography, Optical Coherence (methods)
• Visual Acuity
• Vitrectomy