Effect of 52 % low-sodium salt applied to CM-DASH Diet on atherosclerotic cardiovascular disease risks in patients with hypertension and type-2 diabetes.

Abstract

Introduction:

Introduction: hypertension and diabetes are chronic disorders associated with an increased risk of cardiovascular disease. Objectives: to evaluate the effect of 52 % low-sodium salt applied to the Chinese-modified DASH (CM-DASH) diet on risk of atherosclerotic cardiovascular disease (ASCVD) in patients with hypertension and type-2 diabetes. Methods: the low-sodium salt group (LSSG) took 5 g/day of 52 % low-sodium salt plus CM-DASH diet for 8 weeks, while the normal-sodium salt group (NSSG) took the same dose of normal-sodium salt plus CM-DASH diet for 8 weeks. Blood tests, 24-hour urine tests, anthropometric measurements, and 10-year risk of ASCVD prediction were assessed. Results: compared with baseline, both LSSG and NSSG showed a significant reduction in 10-year risk of ASCVD, but we did not find any statistically significant differences in 10-year risk of ASCVD between LSSG and NSSG. Conclusions: our study shows that salt limits and DASH diets reduce the risk of cardiovascular disease whereas low-sodium salt containing 52 % sodium chloride did not significantly lower the risk of cardiovascular disease when compared to regular salt. Due to the limitations of the research, additional studies will be necessary to confirm our findings.

• Authors: Jie Tang, Dan Chen, Lisha Mu, Pingping Yu, Tao Gong, Huini Xu, Ziyan Zhang, Shuwen Cai, Lihong Mu, Ying Mei
• Journal: Nutricion hospitalaria (Nutr Hosp) Vol. 39 Issue 4 Pg. 778-785 (Aug 25 2022) ISSN: 1699-5198 [Electronic] Spain
• Vernacular Title: Efecto de un 52 % de sal baja en sodio en la dieta CM-DASH sobre el riesgo de enfermedad cardiovascular aterosclerótica en pacientes con hipertensión arterial y diabetes de tipo 2.
• PMID: 35815751 (Publication Type: Journal Article)

Chemical References

• Sodium Chloride, Dietary
• Sodium Chloride
• Sodium

Topics

• Atherosclerosis (epidemiology)
• Blood Pressure
• Cardiovascular Diseases (complications, etiology)
• Diabetes Mellitus, Type 2 (complications)
• Diet
• Diet, Sodium-Restricted
• Dietary Approaches To Stop Hypertension
• Humans
• Hypertension (etiology)
• Sodium
• Sodium Chloride (pharmacology)
• Sodium Chloride, Dietary (adverse effects)