An autopsy case report of fulminant myocarditis: Following mRNA COVID-19 vaccination.

Abstract

There have been few case reports on fatal outcomes in patients with acute myocarditis after mRNA coronavirus disease 2019 (COVID-19) vaccination. In most cases of myocarditis after mRNA COVID-19 vaccination, the myocarditis is mild, and the prognosis is good. Here we report an autopsy case of fulminant myocarditis following mRNA COVID-19 vaccination.

Learning objective:

The global distribution of the mRNA coronavirus disease 2019 vaccine requires consideration of appropriate treatment for postvaccination myocarditis. Eosinophil-mediated immunological injury to cardiomyocytes can be involved in the cause of fulminant inflammation from the pathological findings of postvaccination myocarditis.

• Authors: Naoki Hoshino, Masanobu Yanase, Taisuke Ichiyasu, Kazuhiko Kuwahara, Hideki Kawai, Takashi Muramatsu, Hideki Ishii, Tetsuya Tsukamoto, Shin-Ichiro Morimoto, Hideo Izawa
• Journal: Journal of cardiology cases (J Cardiol Cases) Vol. 26 Issue 6 Pg. 391-394 (Dec 2022) ISSN: 1878-5409 [Electronic] Japan
• PMID: 35812802 (Publication Type: Case Reports)
• Copyright: © 2022 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.