An unusually "complex" glomerulonephritis.

Abstract

A 53-year-old man with granulomatosis with polyangiitis presented with fever and acute kidney injury with nephrotic-range proteinuria following the second dose of the mRNA COVID-19 vaccine. Renal biopsy revealed an unexpected immune complex-glomerulonephritis (IC-GN) without vasculitis. Further workup found the patient to have HIV that was unmasked following the treatment of IC-GN. This case report explores the possible relationship between COVID-19 vaccines and the immune response in the setting of chronic HIV.

• Authors: Gabriela Martinez-Zayas, Daniel Savino, Sumit Kumar, Kathryn H Dao
• Journal: Proceedings (Baylor University. Medical Center) (Proc (Bayl Univ Med Cent)) Vol. 35 Issue 4 Pg. 531-533 ( 2022) ISSN: 0899-8280 [Print] United States
• PMID: 35754562 (Publication Type: Case Reports)
• Copyright: Copyright © 2022 Baylor University Medical Center.