Abstract | BACKGROUND: OBJECTIVE: This study aimed to investigate the prognostic value of the albumin- bilirubin (ALBI) score, a relatively new model for evaluating liver function, in patients with idiopathic DCM. METHODS: A total of 1025 patients with idiopathic DCM were retrospectively included and divided into three groups based on ALBI scores: grade 1 (≤ -2.60, n = 113), grade 2 (-2.60 to -1.39, n = 835), and grade 3 (> -1.39, n = 77). The association of ALBI score with in-hospital major adverse clinical events (MACEs) and long-term mortality was analyzed. P-value less than 0.05 was considered statistically significant. RESULTS: The in-hospital MACEs rate was significantly higher in the grade 3 patients (2.7% versus 7.1% versus 24.7%, p < 0.001). Multivariate analysis showed that ALBI score was an independent predictor for in-hospital MACEs (adjusted odds ratio = 2.80, 95%CI: 1.63 - 4.80, p < 0.001). After a median 27-month follow-up, 146 (14.2%) patients died. The Kaplan-Meier curve indicated that the cumulative rate of long-term survival was significantly lower in patients with higher ALBI grade (log-rank = 45.50, p < 0.001). ALBI score was independently associated with long-term mortality (adjusted hazard ratio = 2.84, 95%CI: 1.95 - 4.13, p < 0.001). CONCLUSION: ALBI score as a simple risk model could be considered a risk-stratifying tool for patients with idiopathic DCM.
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Authors | Mei Jiang, Xue-Biao Wei, Jie-Leng Huang, Ze-da-Zhong Su, Ying-Wen Lin, Dan-Qing Yu |
Journal | Arquivos brasileiros de cardiologia
(Arq Bras Cardiol)
Vol. 118
Issue 6
Pg. 1108-1115
( 2022)
ISSN: 1678-4170 [Electronic] Brazil |
Vernacular Title | Escore Albumina-Bilirrubina para Predizer Desfechos em Pacientes com Cardiomiopatia Dilatada Idiopática. |
PMID | 35703648
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Bilirubin
- Carcinoma, Hepatocellular
- Cardiomyopathy, Dilated
- Humans
- Liver Neoplasms
- Prognosis
- Retrospective Studies
- Serum Albumin
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