Abstract |
Novel NIR-II Ru(II) polypyridyl fluorophore Ru-1 dots for synergistic chemo- photothermal therapy against 4T1 tumors were designed and synthesized. Guided by in vivo NIR-II fluorescence imaging, the synergistic therapeutic efficacy, intracellular delivery, and biodistribution of the Ru-1 dots were precisely tracked in real-time.
|
Authors | Qianqian Li, Yishen Liu, Bingshan Zhao, Jiapeng Lei, Siyu Lu, Wanxia Gong, Ke Liang, Junzhu Wu, Xuechuan Hong, Yuling Xiao |
Journal | Chemical communications (Cambridge, England)
(Chem Commun (Camb))
Vol. 58
Issue 45
Pg. 6546-6549
(Jun 01 2022)
ISSN: 1364-548X [Electronic] England |
PMID | 35579558
(Publication Type: Journal Article)
|
Chemical References |
- Fluorescent Dyes
- Ruthenium
|
Topics |
- Cell Line, Tumor
- Fluorescent Dyes
- Nanoparticles
- Phototherapy
(methods)
- Photothermal Therapy
- Ruthenium
- Tissue Distribution
|