Incidence of and risk factors for self-load-related and medical device-related pressure injuries in critically ill patients: A prospective observational cohort study.

Abstract

There are two types of pressure injuries: self-load-related pressure injuries (PIs) and medical device-related pressure injuries (MDRPIs), but the differences in risk factors between PIs and MDRPIs have not yet been clarified. If risk factors for PIs and MDRPIs differ, preventive interventions should take this into account. This is a prospective cohort study aimed to determine the cumulative incidence of PIs and MDRPIs in critically ill patients and to identify corresponding risk factors. The study included 1418 patients who were admitted to the critical care medical center of a single university hospital in Tokyo, Japan, between 1 December 2019 and 31 August 2020. The Kaplan-Meier method was used to calculate the cumulative incidence of PIs and MDRPIs. Furthermore, the Cox proportional hazards model was used to analyse the predictors in both the PI and MDRPI incidence and non-incidence groups. Predictors were based on data from the 0th disease day. The cumulative incidence of PIs and MDRPIs was 4.6/1000 person-days and 3.6/1000 person-days, respectively. Multivariate analysis using the Cox proportional hazards model showed that common risk factors for the occurrence of PIs and MDRPIs were possession of PI on admission, higher blood lactate, blood purification therapy, and positional restriction. The risk factors for PIs only were diabetes mellitus, septic shock, and a lower serum albumin level, while the risk factors for MDRPIs only were the D-dimer level and extracorporeal membranous oxygenation treatment. Therefore, prophylactic interventions need to consider these different risk factors.

• Authors: Tomoko Shimura, Gojiro Nakagami, Rei Ogawa, Shimpei Ono, Toshiaki Takahashi, Misako Nagata, Kosuke Kashiwabara, Junko Sugama, Hiromi Sanada, Makoto Oe
• Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society (Wound Repair Regen) Vol. 30 Issue 4 Pg. 453-467 (07 2022) ISSN: 1524-475X [Electronic] United States
• PMID: 35567569 (Publication Type: Journal Article, Observational Study)
• Copyright: © 2022 The Wound Healing Society.

Topics

• Critical Illness
• Humans
• Incidence
• Pressure Ulcer (epidemiology, etiology, prevention & control)
• Prospective Studies
• Risk Factors
• Wound Healing