Abstract | BACKGROUND: This study aims to clarify whether myocardial bridge (MB) could influence atherosclerotic plaque characteristics assessed using near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) imaging. METHODS: One hundred and sixteen patients who underwent percutaneous coronary intervention (PCI) using NIRS-IVUS imaging were included. MB was defined as an echo-lucent band surrounding left anterior descending artery (LAD). In MB patients, LAD was divided into three segments: proximal, MB, and distal segments. In non-MB patients, corresponding three segments were defined based on the average length of the above segments. Segmental maximum plaque burden and lipid content derived from NIRS-IVUS imaging in the section of maximum plaque burden were evaluated in each segment. Lipid content of atherosclerotic plaque was evaluated as lipid core burden index (LCBI) and maxLCBI4mm. LCBI is the fraction of pixels indicating lipid within a region multiplied by 1000, and the maximum LCBI in any 4-mm region was defined as maxLCBI4mm. RESULTS: MB was identified in 42 patients. MB was not associated with maximum plaque burden in proximal segment. LCBI and maxLCBI4mm were significantly lower in patients with MB than those without in proximal segment. Multivariable analysis demonstrated both MB and maximum plaque burden in proximal segment to be independent predictors of LCBI in proximal segment. CONCLUSIONS:
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Authors | Kan Saito, Hideki Kitahara, Takaaki Mastuoka, Naoto Mori, Kazuya Tateishi, Yoshihide Fujimoto, Yoshio Kobayashi |
Journal | Heart and vessels
(Heart Vessels)
Vol. 37
Issue 10
Pg. 1701-1709
(Oct 2022)
ISSN: 1615-2573 [Electronic] Japan |
PMID | 35488911
(Publication Type: Journal Article)
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Copyright | © 2022. Springer Japan KK, part of Springer Nature. |
Chemical References |
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Topics |
- Coronary Angiography
- Coronary Artery Disease
(diagnostic imaging, surgery)
- Coronary Vessels
(chemistry, diagnostic imaging)
- Humans
- Lipids
(analysis)
- Percutaneous Coronary Intervention
- Plaque, Atherosclerotic
(diagnosis)
- Predictive Value of Tests
- Spectroscopy, Near-Infrared
- Ultrasonography, Interventional
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