Relieving postoperative pain using tumescent solution with ropivacaine in follicular unit excision.

Abstract

BACKGROUND:

Local tumescent anesthesia relieves postoperative pain.

OBJECTIVE:

The objective of the study was to compare the effect of injecting a tumescent solution with/without ropivacaine on postoperative pain.

METHODS:

A randomized, double-blind control study was conducted in 314 patients who underwent first follicular unit excision after obtaining informed consent and ethics committee approval. The patients were randomly divided into three groups: intra-groups (group 1, injected with tumescent solution with ropivacaine; group 2, without ropivacaine) and inter-group (group 3, right-head/left-head side with/without ropivacaine). Postoperative pain was recorded using the 5-point Wong-Baker Faces Pain Scale. No preoperative analgesic was administered to any patient. The survival rate of hair follicles was measured using dermoscopy during follow-up. Data were statistically analyzed.

RESULTS:

Of the 314 patients included in the study, 166 were men and 148 were women with a mean age of 32.15 ± 4.58 (range, 25-45) years. Postoperative pain with ropivacaine was significantly more relieved compared with that without ropivacaine in both groups (p < 0.05). There was no significant difference between sex and survival rate of hair follicles in the intra- or inter-group.

CONCLUSION:

A tumescent solution with ropivacaine has proven to relieve postoperative pain and is a safe and valuable form of local anesthesia in follicular unit excision.

• Authors: Da-Mao Dai, Qian Qu, Zhe-Xiang Fan, Zhi-Qi Hu, Yong Miao
• Journal: Journal of cosmetic dermatology (J Cosmet Dermatol) Vol. 21 Issue 10 Pg. 4697-4702 (Oct 2022) ISSN: 1473-2165 [Electronic] England
• PMID: 35441795 (Publication Type: Randomized Controlled Trial, Journal Article)
• Copyright: © 2022 Wiley Periodicals LLC.

Chemical References

• Ropivacaine
• Anesthetics, Local
• Amides

Topics

• Male
• Humans
• Female
• Adult
• Ropivacaine
• Anesthetics, Local
• Amides
• Pain, Postoperative (diagnosis, drug therapy, etiology)
• Anesthesia, Local
• Double-Blind Method