Erythema nodosum induced by Covid-19 Pfizer-BioNTech mRNA vaccine: A case report and brief literature review.

Abstract

Erythema nodosum (EN), the most common form of panniculitis, is a reactive inflammation of the subcutaneous fat clinically presented with a sudden onset of painful, erythematous, nodular, subcutaneous lesions, typically localized to the pretibial area. EN is commonly caused by numerous infections (especially beta-haemolytic streptococcal infections), autoimmune diseases (sarcoidosis), inflammatory bowel conditions and drugs. EN induced by Covid-19 vaccines is rarely reported. We describe an original clinical observation of a 75-year-old woman who presented with EN after receiving the second dose of BNT162b2, an mRNA vaccine.

• Authors: Ferdaous Chahed, Najah Ben Fadhel, Haifa Ben Romdhane, Monia Youssef, Seifeddine Ben Hammouda, Amel Chaabane, Karim Aouam, Nadia Ben Fredj
• Journal: British journal of clinical pharmacology (Br J Clin Pharmacol) Vol. 89 Issue 2 Pg. 536-540 (02 2023) ISSN: 1365-2125 [Electronic] England
• PMID: 35434826 (Publication Type: Case Reports, Review)
• Copyright: © 2022 British Pharmacological Society.

Chemical References

• BNT162 Vaccine
• COVID-19 Vaccines

Topics

• Aged
• Female
• Humans
• Autoimmune Diseases (complications)
• BNT162 Vaccine
• COVID-19 (prevention & control, complications)
• COVID-19 Vaccines (adverse effects)
• Erythema Nodosum (chemically induced, diagnosis)