[Therapy of duodenal ulcer using cimetidine].

Abstract

55 patients with endoscopically confirmed duodenal ulcers received either cimetidine (26 patients) or placebo (29 patients) in a double-blind trial. At four weeks, 85% of the patients treated with cimetidine and 62% of those receiving placebo had endoscopically healed ulcers. This difference is not statistically significant. However, patients on cimetidine showed a more rapid and statistically significant reduction in the size of their ulcers.

• Authors: J J Gonvers, R Birchler, J R Hofstetter, S Pelloni, H R Koelz, A L Blum
• Journal: Schweizerische medizinische Wochenschrift (Schweiz Med Wochenschr) Vol. 108 Issue 28 Pg. 1081-3 (Jul 15 1978) ISSN: 0036-7672 [Print] Switzerland
• Vernacular Title: Traitement de l'ulcère duodénal par la cimétidine.
• PMID: 353973 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Guanidines
• Placebos
• Cimetidine

Topics

• Cimetidine (therapeutic use)
• Clinical Trials as Topic
• Double-Blind Method
• Duodenal Ulcer (drug therapy)
• Guanidines (therapeutic use)
• Humans
• Placebos