Available and affordable complementary treatments for COVID-19: From hypothesis to pilot studies and the need for implementation.

Abstract

Vaccination is a highly effective preventive measure against COVID-19. However, complementary treatments are needed to better control the disease. Fermented vegetables and spices, agonists of the antioxidant transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and TRPA1/V1 channels (Transient Receptor Potential Ankyrin 1 and Vanillin 1), may help in the control of COVID-19. Some preliminary clinical trials suggest that curcumin (spice) can prevent some of the COVID-19 symptoms. Before any conclusion can be drawn and these treatments recommended for COVID-19, the data warrant confirmation. In particular, the benefits of the foods need to be assessed in more patients, through research studies and large trials employing a double-blind, placebo-controlled design.

• Authors: Jean Bousquet, Tari Haahtela, Hubert Blain, Wienczyslawa Czarlewski, Torsten Zuberbier, Anna Bedbrook, Alvaro A Cruz, Joao A Fonseca, Ludger Klimek, Piotr Kuna, Boleslaw Samolinski, Arunas Valiulis, Antoine Lemaire, Josep M Anto
• Journal: Clinical and translational allergy (Clin Transl Allergy) Vol. 12 Issue 3 Pg. e12127 (Mar 2022) ISSN: 2045-7022 [Print] England
• PMID: 35344297 (Publication Type: Journal Article)
• Copyright: © 2022 The Authors. Clinical and Translational Allergy published by John Wiley & Sons Ltd on behalf of European Academy of Allergy and Clinical Immunology.