Abstract | Background: Vaccination against Streptococcus pneumoniae (pneumococcus) and Haemophilus influenzae type b (Hib) is not included in China's national immunization programme. To inform China's immunization polices, we estimated annual national, regional, and provincial childhood mortality and morbidity attributable to pneumococcus and Hib in 2010-17. Methods: Findings: In 2010-17, annual pneumococcal deaths fell by 49% from 15 600 (uncertainty range: 10 800-17 300) to 8 000 (5 500-8 900), and Hib deaths fell by 56% from 6 500 (4 500-8 800) to 2 900 (2 000-3 900). Severe pneumococcal and Hib cases decreased by 16% to 218 200 (161 500-252 200) in 2017 and 29% to 49 900 (29 000-99 100). Estimated 2017 national three-dose coverage in private market was 1·3% for PCV and 33·4% for Hib vaccine among children aged 1-59 months. Provinces in the west region had the highest disease burden. Interpretation: Childhood mortality and morbidity attributable to pneumococcal and Hib has decreased in China, but still substantially varied by region and province. Higher vaccine coverage could further reduce disease burden. Funding: Bill & Melinda Gates Foundation.
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Authors | Xiaozhen Lai, Brian Wahl, Wenzhou Yu, Tingting Xu, Haijun Zhang, Cristina Garcia, Ying Qin, Yan Guo, Zundong Yin, Maria Deloria Knoll, Hai Fang |
Journal | The Lancet regional health. Western Pacific
(Lancet Reg Health West Pac)
Vol. 22
Pg. 100430
(May 2022)
ISSN: 2666-6065 [Electronic] England |
PMID | 35308577
(Publication Type: Journal Article)
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Copyright | © 2022 The Author(s). |