An Israeli national survey on ischemic colitis induced by pre-colonoscopy bowel preparation (R1).

Abstract

Background and study aims:

Ischemic colitis (IC) may occur as a complication of colonoscopy. The aim of this study was to characterize patients with IC that occurred after exposure to bowel preparation laxatives, prior to an elective colonoscopy.

Patients and methods:

A survey among Israeli gastroenterologists. Information was collected regarding individual cases.

Results:

Eight patients, who developed IC after bisacodyl ingestion that was taken as part of pre-colonoscopy bowel preparation protocol, were reported. In all patients, severe abdominal pain and/or hematochezia started shortly after the ingestion of the first dose of bisacodyl. IC was found in 7 patients during the planned colonoscopy and in 1 patient using computerized tomography. All patients received supportive treatment and recovered.

Conclusions:

IC induced by bisacodyl is a rare phenomenon. Regardless of being rare, we would advise withholding bisacodyl bowel preparation in elderly subjects with risk factors for IC that are scheduled for a colonoscopy.

• Authors: O Tomer, Y Shapira, O Kriger-Sharabi, N Mawasi, E Melzer, J Epshtein, Z Ackerman
• Journal: Acta gastro-enterologica Belgica (Acta Gastroenterol Belg) 2022 Jan-Mar Vol. 85 Issue 1 Pg. 94-96 ISSN: 1784-3227 [Print] Belgium
• PMID: 35304999 (Publication Type: Journal Article)
• Copyright: © Acta Gastro-Enterologica Belgica.

Chemical References

• Cathartics
• Laxatives
• Bisacodyl

Topics

• Aged
• Bisacodyl (adverse effects)
• Cathartics (adverse effects)
• Colitis, Ischemic (chemically induced, etiology)
• Colonoscopy (adverse effects, methods)
• Humans
• Laxatives