Generation of iPS cell line (ICGi040-A) from skin fibroblasts of a patient with ring small supernumerary marker chromosome 4.

Abstract

Human induced pluripotent stem cell (iPSC) line, ICGi040-A, was obtained from skin fibroblasts derived from a male patient with mosaic ring small supernumerary marker chromosome 4 (sSMS(4)) and infertility. ICGi040-A cells have karyotype 47,XY,+r(4) in 97% of cells and express a set of pluripotent markers, as well as are able to differentiate in vitro into derivatives of all three embryonic germ layers.

• Authors: M M Gridina, A R Nurislamov, J M Minina, M E Lopatkina, G V Drozdov, S A Vasilyev, L I Minaycheva, E O Belyaeva, T V Nikitina, A A Kashevarova, I N Lebedev, T V Karamysheva, N B Rubtsov, O L Serov
• Journal: Stem cell research (Stem Cell Res) Vol. 61 Pg. 102740 (05 2022) ISSN: 1876-7753 [Electronic] England
• PMID: 35303600 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.

Topics

• Cell Line
• Chromosomes, Human, Pair 4
• Fibroblasts (metabolism)
• Humans
• Induced Pluripotent Stem Cells (metabolism)
• Karyotype
• Male