Abstract |
Lung transplantation (LTx) using donation after circulatory death ( DCD) donors has demonstrated equivalent outcomes compared to donation after brain dead (DBD) donors. However, data from the use of DCDs for high-risk (HR) recipients is limited. We performed a propensity match study to evaluate the impact of DCD transplantation on HR recipients. In addition, we assessed the effect of recipient profile (HR vs. non-HR) in DCDs and DBDs LTx. From 2009-2018, 1829 double lung transplants (DLTx) for HR recipients were identified. Of these, 131 were performed using DCD donors. There was no difference in survival between DCDs and DBDs among HR-DLTx recipients (p = 0.16). However, HR recipients had worse survival compared to non-HR recipients in DBD (p < 0.001) but not in DCD transplantation (p = 0.95). Our findings support that DCD lungs are appropriate for HR recipients and should not be considered inferior or higher-risk donors. Its use should be further stimulated rather than restricted.
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Authors | Pedro Augusto Reck Dos Santos, Paulo José Zimermann Teixeira, Daniel Messias de Moraes Neto, Blake Langlais, Marcelo Cypel |
Journal | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
(J Heart Lung Transplant)
Vol. 41
Issue 6
Pg. 712-715
(06 2022)
ISSN: 1557-3117 [Electronic] United States |
PMID | 35300913
(Publication Type: Journal Article)
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Copyright | Copyright © 2022 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved. |
Topics |
- Brain Death
- Death
- Graft Survival
- Humans
- Lung Transplantation
- Registries
- Retrospective Studies
- Tissue Donors
- Tissue and Organ Procurement
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