Abstract |
Mycobacterium kansasii is the second most common cause of nontuberculous mycobacterial (NTM) lung disease after Mycobacterium avium complex infection in the United States.[1] The first-line therapy for M. kansasii is a three- drug regimen including rifampin, isoniazid, and ethambutol. We present a case of a patient with pulmonary M. kansasii who developed bullous skin lesions while receiving this regimen and again after rechallenge with ethambutol. In patients with intolerance to one of the first-line antibiotics, a multidisciplinary team approach to starting second-line agents is needed. Ethambutol should be included in the differential diagnosis of drug-induced bullous skin lesions in treated patients with NTM, who develop new onset rash with blisters or ulceration.
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Authors | Venkateswara K Kollipara, Mitchell Horowitz, Jeffery Lantz, Stephanie Nagy-Agren |
Journal | International journal of mycobacteriology
(Int J Mycobacteriol)
2022 Jan-Mar
Vol. 11
Issue 1
Pg. 120-122
ISSN: 2212-554X [Electronic] India |
PMID | 35295035
(Publication Type: Case Reports)
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Chemical References |
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Topics |
- Ethambutol
(pharmacology)
- Humans
- Isoniazid
(pharmacology)
- Lung
- Mycobacterium Infections, Nontuberculous
(diagnosis, drug therapy, microbiology)
- Mycobacterium avium-intracellulare Infection
(drug therapy)
- Mycobacterium kansasii
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