Abstract | BACKGROUND: METHODS: A total of 144 patients who underwent pancreaticoduodenectomy were divided into 2 groups according to the performed pancreaticojejunostomy technique (modified Blumgart anastomosis, n = 91 and traditional anastomosis, n = 53). Preoperative clinicodemographic data, perioperative findings, and postoperative results were compared between the groups. Additionally, factors associated with clinically relevant postoperative pancreatic fistula were analyzed. RESULTS: The modified Blumgart anastomosis group had lower clinically relevant postoperative pancreatic fistula rate than traditional anastomosis group (n = 8 (8.8%) versus n = 14 (26.4%), P = .005). On the contrary, the biochemical leakage rate was higher in the modified Blumgart anastomosis group ( n = 30 (33%) versus n = 9 (17%), P = .037). While postoperative pancreatic fistula-related reoperation rate was lower (n = 2 (2.2%) versus n = 7 (13.2%), P = .013), the length of hospital stay was also shorter (11 days (5-47 days) versus 21 days (6-46 days), P < .001) in the modified Blumgart anastomosis group. Univariate and multivariate analyses revealed that modified Blumgart anastomosis was an independent and negative predictive factor for clinically relevant postoperative pancreatic fistula (odds ratio = 0.274, 95% confidence interval = 0.103-0.728, P = .009). CONCLUSION: Compared to the traditional anastomosis, modified Blumgart anastomosis decreases the rate of transition from biochemical leakage to clinically relevant postoperative pancreatic fistula and postoperative pancreatic fistula-related reoperation and also shortens the length of hospital stay. In addition, modified Blumgart anastomosis is an independent and negative predictive factor for the development of clinically relevant postoperative pancreatic fistula.
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Authors | Oğuzhan Özşay, Mehmet Can Aydın |
Journal | The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
(Turk J Gastroenterol)
Vol. 33
Issue 2
Pg. 119-126
(02 2022)
ISSN: 2148-5607 [Electronic] Turkey |
PMID | 35238780
(Publication Type: Journal Article)
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Topics |
- Anastomosis, Surgical
(adverse effects, methods)
- Humans
- Pancreatic Fistula
(epidemiology, etiology, prevention & control)
- Pancreaticoduodenectomy
(adverse effects, methods)
- Pancreaticojejunostomy
(adverse effects, methods)
- Postoperative Complications
(etiology, surgery)
- Treatment Outcome
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