HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Curative efficacy of surgical procedures for older patients with femoral neck fracture: a network meta-analysis and systematic review.

AbstractBACKGROUND:
Femoral neck fractures have a higher incidence in older people with poor prognosis, inducing serious social problems. Common treatment methods include total hip arthroplasty, bipolar hemiarthroplasty, double-screw fixation, multiple-screw fixation, and dynamic hip system.
METHODS:
We searched through four electronic databases, including PubMed, Web of Science, Cochrane Library, and Embase databases, for articles regarding femoral neck fractures, bone screw, and hip prosthesis published up to February 11, 2020. All included articles were used for quality evaluation and data extraction. Extracted data were expressed as odds ratios or weighted mean differences, with 95% confidence intervals. We conducted a network meta-analysis for Harris hip score, complications, 1-year mortality rate, reoperation rate, intraoperative blood loss, and duration of operation using STATA version 16.0 software.
RESULTS:
Twenty-two randomized controlled trials and nine cohort studies included in this study involved 3861 patients. Total hip arthroplasty significantly improved the postoperative function of patients with femoral neck fractures. The surface under the cumulative ranking curve value of the Harris hip score for more than 1 year after total hip arthroplasty was 98.2.
CONCLUSIONS:
This meta-analysis indicated no significant difference in mortality among different treatment groups. Total hip arthroplasty can provide satisfactory outcomes in hip joint function, and double-screw fixation results in the lowest intraoperative risk. In general, total hip arthroplasty results in a lower incidence of adverse events and is especially recommended for patients with femoral neck fractures. This article has been retrospectively registered on the International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY) on November 27, 2020. Registration number: INPLASY2020110123.
AuthorsLanxin Cui, Shishun Zhao, Heng Tian, Wenlai Guo, Xiaoming Dong
JournalJournal of orthopaedic surgery and research (J Orthop Surg Res) Vol. 17 Issue 1 Pg. 127 (Mar 02 2022) ISSN: 1749-799X [Electronic] England
PMID35236384 (Publication Type: Journal Article, Systematic Review)
Copyright© 2022. The Author(s).
Topics
  • Aged
  • Aged, 80 and over
  • Arthroplasty, Replacement, Hip (methods)
  • Female
  • Femoral Neck Fractures (mortality, surgery)
  • Hemiarthroplasty (methods)
  • Humans
  • Male
  • Network Meta-Analysis
  • Randomized Controlled Trials as Topic
  • Reoperation
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: