Abstract | BACKGROUND: METHODS: We will follow the scoping review framework developed by Arksey and O'Malley. MEDLINE (via PubMed), EMBASE, and the Cochrane Central Register of Controlled Trials will be searched for relevant English-language publications, and only peer-reviewed, controlled comparative in vivo/in-vitro/human studies examining the effects of herbs on respiratory disease induced by PM will be included. The basic characteristics, research methods, detailed regimens, possible mechanisms, outcomes, and results will be extracted using a predefined standardized data extraction form. Outcomes will be presented in the following categories: pulmonary function, inflammatory markers, reactive oxygen species, histology and mechanisms, and adverse events. Two researchers will independently perform the study selection, data extraction, and quality assessment. We will also present the research map and implications for further study. ETHICS AND DISSEMINATION: Ethical approval is not required because individual patient data will not be included. The findings will be disseminated through peer-reviewed publications or conference presentations. SYSTEMATIC REVIEW REGISTRATION: This review protocol has been registered with the Open Science Framework on February 12, 2021 ( https://osf.io/s7uvk/ ).
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Authors | Jungtae Leem, Yohwan Kim, Kwan-Il Kim |
Journal | Systematic reviews
(Syst Rev)
Vol. 11
Issue 1
Pg. 35
(Mar 01 2022)
ISSN: 2046-4053 [Electronic] England |
PMID | 35232461
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2022. The Author(s). |
Chemical References |
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Topics |
- Clinical Protocols
- Herbal Medicine
- Humans
- Particulate Matter
(toxicity)
- Plants, Medicinal
- Research Design
- Review Literature as Topic
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