Abstract | BACKGROUND: METHODS: Data from 117 cases of lung metastasis after pancreatectomy were collected retrospectively from 23 institutions in Japan. To compare the sites of metastasis we also collected the data of 134 patients with liver only metastasis, 67 patients with peritoneal only metastasis and 121 patients with locoregional recurrence alone. RESULTS: In patients with lung only metastasis, the median time from recurrence to death (RTD) was 23.1 months, which was better in comparison to other sites of recurrence. In lung metastasis group, the patients who underwent pulmonary resection had better long-term outcomes in comparison to those who did not. (RTD: 29.2 vs 15.2, P < .001). In the multivariate analysis, solitary metastasis (HR 5.03; 95% CI 1.195-21.144, P = .022) and postoperative chemotherapy (HR 14.089; 95% CI 1.729-114.77, P = .023) were identified as significant prognostic factors after lung resection. CONCLUSIONS:
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Authors | Yuki Homma, Itaru Endo, Ryusei Matsuyama, Masayuki Sho, Shugo Mizuno, Yasuji Seyama, Satoshi Hirano, Takashi Aono, Chie Kitami, Yoshifumi Morita, Yutaka Takeda, Kazuhiro Yoshida, Masaji Tani, Takashi Kaiho, Yuzo Yamamoto, Hideki Aoki, Masao Ogawa, Takefumi Niguma, Yuko Mataki, Hiroshi Kawasaki, Hideo Baba, Hiroshi Yokomizo, Toshiki Rikiyama, Hiroki Yamaue, Masakazu Yamamoto |
Journal | Journal of hepato-biliary-pancreatic sciences
(J Hepatobiliary Pancreat Sci)
Vol. 29
Issue 5
Pg. 552-561
(May 2022)
ISSN: 1868-6982 [Electronic] Japan |
PMID | 35179827
(Publication Type: Journal Article, Multicenter Study)
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Copyright | © 2022 Japanese Society of Hepato-Biliary-Pancreatic Surgery. |
Topics |
- Carcinoma, Pancreatic Ductal
(drug therapy, surgery)
- Humans
- Liver Neoplasms
(surgery)
- Lung Neoplasms
(secondary, surgery)
- Neoplasm Recurrence, Local
(surgery)
- Pancreatectomy
- Pancreatic Neoplasms
(pathology)
- Prognosis
- Retrospective Studies
- Survival Rate
- Pancreatic Neoplasms
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