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Phase I trials of the lysine-specific demethylase 1 inhibitor, GSK2879552, as mono- and combination-therapy in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes.

AuthorsGail J Roboz, Karen Yee, Amit Verma, Gautam Borthakur, Adolfo de la Fuente Burguera, Guillermo Sanz, Helai P Mohammad, Ryan G Kruger, Natalie O Karpinich, Geraldine Ferron-Brady, Andre Acusta, Heather Del Buono, Therese Collingwood, Marc Ballas, Arindam Dhar, Andrew H Wei
JournalLeukemia & lymphoma (Leuk Lymphoma) Vol. 63 Issue 2 Pg. 463-467 (02 2022) ISSN: 1029-2403 [Electronic] United States
PMID34927529 (Publication Type: Clinical Trial, Phase I, Letter, Research Support, Non-U.S. Gov't)
Chemical References
  • Benzoates
  • Cyclopropanes
  • GSK2879552
  • Lysine
Topics
  • Benzoates
  • Cyclopropanes
  • Humans
  • Leukemia, Myeloid, Acute (drug therapy)
  • Lysine
  • Myelodysplastic Syndromes (drug therapy)

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