Predicting High-Value Care Outcomes After Surgery for Non-Skull Base Meningiomas.

Abstract

OBJECTIVE:

A need exists to better understand the prognostic factors that influence high-value care outcomes after meningioma surgery. The goal of the present study was to develop predictive models to determine the patients at risk of experiencing an extended hospital length of stay (LOS), nonroutine discharge disposition, and/or a 90-day hospital readmission after non-skull base meningioma resection.

METHODS:

In the present study, we analyzed the data from 396 patients who had undergone surgical resection of non-skull base meningiomas at a single institution between January 1, 2005 and December 31, 2020. The Mann-Whitney U test was used for bivariate analysis of the continuous variables and the Fisher exact test for bivariate analysis of the categorical variables. A multivariate analysis was conducted using logistic regression models.

RESULTS:

Most patients had had a falcine or parasagittal meningioma (66.2%), with the remainder having convexity (31.8%) or intraventricular (2.0%) tumors. Nonelective surgery (P < 0.0001) and an increased tumor volume (P = 0.0022) were significantly associated with a LOS >4 days on multivariate analysis. The independent predictors of a nonroutine discharge disposition included male sex (P = 0.0090), nonmarried status (P = 0.024), nonelective surgery (P = 0.0067), tumor location within the parasagittal or intraventricular region (P = 0.0084), and an increased modified frailty index score (P = 0.039). Hospital readmission within 90 days was independently associated with nonprivate insurance (P = 0.010) and nonmarried status (P = 0.0081). Three models predicting for a prolonged LOS, nonroutine discharge disposition, and 90-day readmission were implemented in the form of an open-access, online calculator (available at: https://neurooncsurgery3.shinyapps.io/non_skull_base_meningiomas/).

CONCLUSIONS:

After external validation, our open-access, online calculator could be useful for assessing the likelihood of adverse postoperative outcomes for patients undergoing surgery of non-skull base meningioma.

• Authors: Adrian E Jimenez, Sachiv Chakravarti, Sophie Liu, Esther Wu, Oren Wei, Pavan P Shah, Sumil Nair, Julian L Gendreau, Jose L Porras, Tej D Azad, Christopher M Jackson, Gary Gallia, Chetan Bettegowda, Jon Weingart, Henry Brem, Debraj Mukherjee
• Journal: World neurosurgery (World Neurosurg) Vol. 159 Pg. e130-e138 (Mar 2022) ISSN: 1878-8769 [Electronic] United States
• PMID: 34896348 (Publication Type: Journal Article)
• Copyright: Copyright © 2021 Elsevier Inc. All rights reserved.

Topics

• Humans
• Length of Stay
• Male
• Meningeal Neoplasms (surgery)
• Meningioma (surgery)
• Patient Readmission
• Retrospective Studies