A case of polyneuropathy associated with diabetic ketoacidosis in new-onset type 1 diabetes.

Abstract

Although diabetic peripheral neuropathy is the most common diabetic microangiopathic complication, several other neuropathy syndromes can occur in the context of diabetes. We describe a rare case of polyneuropathy associated with diabetic ketoacidosis in a patient with new-onset type 1 diabetes. A 42-year-old man with diabetic ketoacidosis was admitted to our hospital with complications of respiratory and renal failure requiring mechanical ventilation and hemodialysis, respectively. After diabetic ketoacidosis improved from the critical state, he developed upper- and lower-limb paralysis with sensory disturbances and pain, as well as right facial paralysis, left recurrent nerve paralysis, and left hypoglossal nerve paralysis. Autonomic nerve function was also impaired. As the pathophysiology, prevention, and treatment of polyneuropathy associated with diabetic ketoacidosis are unclear, the neurologic function of patients with diabetic ketoacidosis should be closely monitored.

• Authors: Kokoro Sada, Shuji Hidaka, Makoto Takemaru, Daisuke Ueno, Hirotaka Shibata
• Journal: Journal of diabetes investigation (J Diabetes Investig) Vol. 13 Issue 5 Pg. 918-922 (May 2022) ISSN: 2040-1124 [Electronic] Japan
• PMID: 34845866 (Publication Type: Case Reports)
• Copyright: © 2021 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.

Topics

• Adult
• Diabetes Mellitus, Type 1 (complications)
• Diabetic Ketoacidosis (complications, therapy)
• Diabetic Neuropathies (complications, therapy)
• Humans
• Male
• Paralysis (complications)
• Polyneuropathies