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Comparison of Magnetic Resonance Imaging of the Lower Uterine Segment in Pregnant Women with Central Placenta Previa with and without Placenta Accreta Spectrum from a Single Center.

Abstract
BACKGROUND Placenta accreta spectrum (PAS) includes placenta increta, placenta percreta, and placenta accreta. PAS is due to abnormal decidualization and can lead to severe maternal hemorrhage and occurs in up to 3% of women with central placental previa (CPP). This study from a single center aimed to compare the magnetic resonance imaging (MRI) changes in the lower uterine segment in pregnant women with CPP, with and without PAS. MATERIAL AND METHODS This retrospective study includes 90 pregnant women with PAS and 66 pregnant women without PAS. All participants were confirmed to have CPP by MRI. Eight MRI parameters were assessed and compared with perinatal outcomes for mothers and newborns. RESULTS The pregnancies in the non-PAS group had less operative time (P=0.001), less intrapartum hemorrhage (P<0.001), and less blood transfusion than the PAS group (P<0.001). The 8 MRI variables with different odds ratios were placenta thickness (4.20), cervical lengths (3.27), placental dark T2 bands area (5.10), cervical marginal sinus (3.04), bladder bulge (3.55), myometrial thinning (6.41), lower uterine segment bulge (4.61), and placental signals in the cervix (9.14). The sensitivity and specificity of MRI in the diagnosis of PAS were 82.22% and 91.09%, respectively, by the combined 8 MRI features, and the area under the curve (AUC) was 0.816. CONCLUSIONS The findings from this study showed that MRI of the lower uterine segment had high sensitivity and specificity for the diagnosis of PAS in pregnant women with CPP.
AuthorsShunyu Hou, Ye Song, Jiahui Wu, Liping Zhou, Suya Kang, Xi Chen, Lei Zhang, Yanli Lu, Yongfei Yue
JournalMedical science monitor : international medical journal of experimental and clinical research (Med Sci Monit) Vol. 27 Pg. e932759 (Oct 22 2021) ISSN: 1643-3750 [Electronic] United States
PMID34675167 (Publication Type: Journal Article)
Topics
  • Adult
  • Female
  • Humans
  • Magnetic Resonance Imaging (methods)
  • Placenta Accreta (diagnostic imaging)
  • Placenta Previa (diagnostic imaging)
  • Pregnancy
  • Prenatal Diagnosis (methods)
  • Retrospective Studies
  • Sensitivity and Specificity

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