Chronic
venous ulcers, often complicated by late diagnosis and
persistent infections, present major clinical and financial challenges. Recently,
photobiomodulation therapy (PBMT) has been shown to be effective in overcoming physiological impairments such as hemostasis and
inflammation, accelerating the wound healing process. This case series summarises our experience in the treatment of two Asian patients with lower-extremity chronic
venous ulcers using PBMT with blue light. Case 1 was a 71-year-old male with a history of
hypertension, chronic
venous insufficiency and previous
deep vein thrombosis. Prior to
blue light therapy, the average
duration of treatment until
wound closure with compression dressings used to be 10-12 weeks. Complete
wound closure with the
blue light therapy was eight weeks, with a total reduction of 67% of
wound size by week 4. Case 2 was a 77-year-old male with a background of
hypertension and ischaemic
heart disease. Prior to
blue light therapy, the patient had also underwent iliac venoplasty and stenting for his recurring bilateral malleolus
venous ulcers. By week 4, the right malleolus
wound had healed, while the left malleolus
wound had a size reduction of 38%. Complete closure of both the
wounds was noted at week 6. Blue light was administered to the
wounds of both patients for 120 seconds per session, as an adjunct to compression
therapy. Both patients reported no additional
wound pain during the administration of
blue light therapy, with an overall reduction of
wound pain at three weeks. The cases demonstrated that PBMT with blue light was well-tolerated, safe, and efficacious in improving wound healing with an adjunct to standard treatment of chronic
venous ulcers.