Peritoneal
metastasis is the most common distant
metastasis of
gastric cancer. As an end-stage event of
gastric cancer, patients with peritoneal
metastasis often have lost the chance of radical resection, and even after palliative surgical resection, the long-term outcomes are still not satisfactory. In recent years, with the application and promotion of laparoscopic technology, neoadjuvant intraperitoneal and systemic
chemotherapy, hyperthermic intraperitoneal chemotherapy and
cytoreductive surgery, through perioperative comprehensive treatment strategies by multidisciplinary team, the quality of life and survival of patients with peritoneal
metastasis have been significantly improved. Some patients with
gastric cancer peritoneal
metastasis diagnosed by laparoscopy even get the opportunity to have radical
cytoreductive surgery and
hyperthermic intraperitoneal chemotherapy after neoadjuvant intraperitoneal and systemic
chemotherapy. Taking into account the progress in the treatment of
gastric cancer peritoneal
metastasis in recent years, this article intends to combine current clinical evidence and to discuss the key issues in the course of clinical diagnosis and treatment of
gastric cancer peritoneal implantation and
metastasis, including the imaging diagnosis of peritoneal
metastasis, laparoscopic examination, evaluation of peritoneal
metastasis and comprehensive treatment plan.