Abstract | OBJECTIVE: METHODS: RESULTS: Response evaluation showed that the number of patients with complete response (CR), partial response (PR), stable disease (SD), and progressive disease (PD) was 0 (0%), 26 (61.9%), 14 (33.3%), and 2 (4.8%), respectively. The CR/PR group (patients with CR or PR) showed higher pC1q (C1q level before immunotherapy) and iC1q (C1q level 3 weeks after immunotherapy) than the SD/PD group (patients with SD or PD). The LDH reduction (96.2%) and C1q increment (84.6%) in the CR/PR group 3 weeks after immunotherapy were higher than those of the SD/PD group, and the differences were statistically significant. Logistic regression analysis indicated that pC1q, iC1q, and LDH level trends 3 weeks after the treatment were significantly correlated to the efficacy of combined immunotherapy with odds ratios of 8.185, 5.500, and 0.031, respectively. CONCLUSION:
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Authors | Daoming Zhang, Yuan Li, Haoyue Li, Tian Tang, Yongfa Zheng, Xufeng Guo, Ximing Xu |
Journal | Cancer management and research
(Cancer Manag Res)
Vol. 13
Pg. 7131-7137
( 2021)
ISSN: 1179-1322 [Print] New Zealand |
PMID | 34531687
(Publication Type: Journal Article)
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Copyright | © 2021 Zhang et al. |