This study presents a new way to investigate comprehensive trends in
cancer nanotechnology research in different countries, institutions, and journals providing critical insights to prevention, diagnosis, and
therapy. This paper applied the qualitative method of bibliometric analysis on
cancer nanotechnology using the PubMed database during the years 2000-2021. Inspired by hybrid medical models and content-based and bibliometric features for machine learning models, our results show
cancer nanotechnology studies have expanded exponentially since 2010. The highest production of articles in
cancer nanotechnology is mainly from US institutions, with several countries, notably the USA, China, the UK, India, and Iran as concentrated focal points as centers of
cancer nanotechnology research, especially in the last five years. The analysis shows the greatest overlap between nanotechnology and
DNA,
RNA,
iron oxide or mesoporous
silica,
breast cancer, and
cancer diagnosis and
cancer treatment. Moreover, more than 50% of the information related to the keywords, authors, institutions, journals, and countries are considerably investigated in the form of publications from the top 100 journals. This study has the potential to provide past and current lines of research that can unmask comprehensive trends in
cancer nanotechnology, key research topics, or the most productive countries and authors in the field.