Bacterial DNA screening to characterize surgical site infection risk in orthopaedic patients.

Abstract

PURPOSE:

To provide an initial characterization of relevant bacterial DNA profiles for patients undergoing closed-fracture fixation or total joint arthroplasties.

PATIENTS AND METHODS:

Swabs were collected and analyzed using Polymerase Chain Reaction from adult patients undergoing closed-fracture fixation or total shoulder, knee, or hip arthroplasties.

RESULTS:

Bacterial DNA profiles varied across the different orthopaedic patient populations, and produced uncharacteristic profile shifts with direct relevance to each clinical infection.

CONCLUSION:

Findings provide a foundational dataset regarding bacterial colonization of relevant anatomic sites that can act as sources of surgical site infections for patients.

• Authors: Preston N Wolfe, Brian D Campfield, Brett D Crist, James A Keeney, Matthew J Smith, James L Cook, Aaron M Stoker
• Journal: Journal of orthopaedics (J Orthop) 2021 Sep-Oct Vol. 27 Pg. 56-62 ISSN: 0972-978X [Print] India
• PMID: 34483551 (Publication Type: Journal Article)
• Copyright: © 2021 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.