Abstract | OBJECTIVE: To compare maternal outcomes using Carbetocin versus Oxytocin for the active management of the third stage of labor, given a temporary national shortage of Oxytocin. METHODS: RESULTS: Incidence rates of placental retention and postpartum hemorrhage were 4.9% and 9.4% respectively. Placenta retention was significantly more likely following Carbetocin administration (adjusted odds ratio 2.5; 95% confidence interval 1.2-5.0). Postpartum hemorrhage rates were not significantly different (adjusted odds ratio 1.1; 95% confidence interval 0.6-2.1), as were severe postpartum hemorrhage rates (adjusted odds ratio 0.7; 95% confidence interval 0.2-2.2). CONCLUSION:
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Authors | Joanna Sichitiu, David Baud, David Desseauve |
Journal | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
(J Matern Fetal Neonatal Med)
Vol. 35
Issue 25
Pg. 8114-8117
(Dec 2022)
ISSN: 1476-4954 [Electronic] England |
PMID | 34470143
(Publication Type: Observational Study, Journal Article)
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Chemical References |
- carbetocin
- Oxytocin
- Oxytocics
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Topics |
- Female
- Humans
- Pregnancy
- Postpartum Hemorrhage
(prevention & control, drug therapy)
- Oxytocin
(therapeutic use)
- Oxytocics
(therapeutic use)
- Placenta
- Placenta, Retained
(prevention & control, drug therapy)
- Postpartum Period
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