Ovarian hyperstimulation syndrome (OHSS) is an exaggerated response to excess
hormones and is also one of the life-threatening iatrogenic complications which is associated with ovulation induction. This syndrome usually occurs in women who receive
injectable hormones for the stimulation of egg development in the ovaries. This study describes a rare case of moderate
ovarian hyperstimulation syndrome which has been managed and treated with high-dose
cabergoline. The patient was diagnosed in the Medical Imaging and Radiation Sciences Department of Kabul University of Medical Sciences and treated in Shahrara Teaching Hospital. A 26-year-old woman was diagnosed with the development of bilateral moderate
ovarian hyperstimulation syndrome after receiving
clomiphene citrate in dose of 100 mg BID on day 5 of period and
Human Chorionic Gonadotropin (HCG) 10,000 units for egg release on day 14 of period. The patient was given a high dose of
cabergoline. The dose was adjusted to 1 mg/day for eight days since she was diagnosed with
ovarian hyperstimulation syndrome. Consequently, the main outcome of our intervention was complete resolution of OHSS as well as complete recovery of the patient. As a result, it is concluded that the high dose of
cabergoline prevents and reduces the occurrence, prolongation, and severity of
ovarian hyperstimulation syndrome. However, more assessments through randomized controlled trials regarding the efficacy and safety of
cabergoline doses and
treatment duration for treatment and preventive purposes are required.