Psoriasis is a chronic inflammatory systemic disease primarily affecting the skin, but which often involves considerable comorbidities as well. One-third of
psoriasis cases start during childhood. In pediatric
psoriasis, an association with several medical comorbidities is also indicated. Furthermore, because of its chronic nature and frequent relapses, psoriatic patients tend to require long-term treatment and experience negative impacts on their quality of life. Considering the different clinical characteristics of pediatric
psoriasis, it has recently been presented that the pathogenesis of pediatric
psoriasis is distinct from adult
psoriasis. Treatment for pediatric
psoriasis usually involves the same methods as for adults. However, most treatments in pediatric
psoriasis are used off-label and research in this regard is still lacking. Targeted
therapies involving newly developed biologics are also increasingly being applied to
psoriasis in children. This review summarizes the clinical characteristics of pediatric
psoriasis and focuses mainly on the updated concepts of pathogenesis and treatments in pediatric
psoriasis. This was undertaken to widen the understanding of these relevant aspects and to provide better management of pediatric
psoriasis by clinicians.